Trials Today

Brain Mechanisms of Reducing Polysubstance Use

Purpose

The proposed study will test whether neurofeedback (NF) could optimize integrative body-mind training (IBMT) practice.

Condition

Multiple Drug Use

Eligibility

Eligible Ages: Over 18 Years
Eligible Sex: All
Accepts Healthy Volunteers: Yes

Inclusion Criteria

At least 18 years old - Free of any psychiatric diagnoses or medication (besides a substance use disorder (SUD) to alcohol, tobacco, or cannabis) - In the past month, at least 4 episodes of heavy episodic drinking; at least 3 occasions of cannabis use; and daily cigarette use for at least the past month - Normal or corrected-to-normal vision - Written informed consent - No previous meditation or NF experiences

Exclusion Criteria

Any psychiatric diagnoses other than an SUD - Medical disorder(s) that may affect the central nervous system; medications that affect the central and autonomic nervous system; or a positive pregnancy test result (females) - Excluding cannabis, evidence of recent (past month) illicit drug use

Study Design

Phase: N/A
Study Type: Interventional
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: mindfulness or/and active/sham neurofeedback
Primary Purpose: Basic Science
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Arm Groups

Arm	Description	Assigned Intervention
Experimental IBMT	An evidence-based preventive intervention - integrative body-mind training (IBMT) has shown positive effects in reducing stress and improving self-control and brain plasticity. It has bodifulness and mindfulness components.	Behavioral: IBMT IBMT is an effortless mindfulness technique
Experimental NF	An evidence-based intervention - NF can not only provide real-time feedback for practice but also target the self-control networks, suggesting the possibility of augmenting IBMT effects via NF.	Behavioral: NF NF is a mental training technique.
Experimental IBMT + NF	The combined IBMT and NF also show positive effects in reducing substance use.	Behavioral: IBMT IBMT is an effortless mindfulness technique Behavioral: NF NF is a mental training technique.
Sham Comparator Sham NF	Sham NF has the same settings as the active NF but does not have correct parameters of stimulation.	Behavioral: NF NF is a mental training technique.

Recruiting Locations

YiYuan Tang
Phoenix, Arizona 85004

Contact:
YiYuan Tang
4807903577
yiyuan@asu.edu

More Details

NCT ID: NCT06324786
Status: Recruiting
Sponsor: Arizona State University

Study Contact

YiYuan Tang
4807903577
yiyuan@asu.edu

Detailed Description

The proposed study will test whether real-time NF could optimize IBMT practice and improve effects in reducing polysubstance use through targeting self-control networks in the brain.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.