Brain Mechanisms of Reducing Polysubstance Use
Purpose
The proposed study will test whether neurofeedback (NF) could optimize integrative body-mind training (IBMT) practice.
Condition
- Multiple Drug Use
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- At least 18 years old - Free of any psychiatric diagnoses or medication (besides a substance use disorder (SUD) to alcohol, tobacco, or cannabis) - In the past month, at least 4 episodes of heavy episodic drinking; at least 3 occasions of cannabis use; and daily cigarette use for at least the past month - Normal or corrected-to-normal vision - Written informed consent - No previous meditation or NF experiences
Exclusion Criteria
- Any psychiatric diagnoses other than an SUD - Medical disorder(s) that may affect the central nervous system; medications that affect the central and autonomic nervous system; or a positive pregnancy test result (females) - Excluding cannabis, evidence of recent (past month) illicit drug use
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Intervention Model Description
- mindfulness or/and active/sham neurofeedback
- Primary Purpose
- Basic Science
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental IBMT |
An evidence-based preventive intervention - integrative body-mind training (IBMT) has shown positive effects in reducing stress and improving self-control and brain plasticity. It has bodifulness and mindfulness components. |
|
|
Experimental NF |
An evidence-based intervention - NF can not only provide real-time feedback for practice but also target the self-control networks, suggesting the possibility of augmenting IBMT effects via NF. |
|
|
Experimental IBMT + NF |
The combined IBMT and NF also show positive effects in reducing substance use. |
|
|
Sham Comparator Sham NF |
Sham NF has the same settings as the active NF but does not have correct parameters of stimulation. |
|
Recruiting Locations
More Details
- NCT ID
- NCT06324786
- Status
- Recruiting
- Sponsor
- Arizona State University
Detailed Description
The proposed study will test whether real-time NF could optimize IBMT practice and improve effects in reducing polysubstance use through targeting self-control networks in the brain.