Purpose

The goal of this clinical trial is to create a vocal health database of people aged 4-65 with no diagnosed voice pathology. The main question it aims to answer is: - what is the best way to assess pediatric voices; and, - what are the differences between healthy and dysphonic pediatric voices? Participants will complete one 60 minute session involving one of three types of aerodynamic interruption.

Condition

Eligibility

Eligible Ages
Between 4 Years and 65 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy Control: - Age 4-65 years - Normal voice - No history of voice or other pertinent health disorders

Exclusion Criteria

  • Healthy Control: - Neuromuscular disorder affecting the larynx - History of respiratory or laryngeal disease - History of smoking - Hearing impairment - Cognitive impairment that might impact ability to perform the tasks required by the study Inclusion Criteria - Abnormal Voice: - Age 4-17 - Laryngeal pathology Exclusion Criteria - Abnormal Voice: - No laryngeal disorder

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Other
Masking
Double (Participant, Care Provider)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Complete airflow interruption
  • Device: Complete airflow interruption
    Participants will produce a sustained vowel into a mouthpiece (with nose-clip) connected to a PVC tube, with a balloon valve
Experimental
Incomplete airflow interruption
  • Device: Incomplete airflow interruption
    Incomplete airflow interruption uses a Y-shaped device. The participant produces a sustained /a/ into a mouthpiece and air filter connected to the tube. The tube splits into two tubes distally.
Experimental
Airflow redirection
  • Device: Airflow redirection
    Participant phonates through a mouthpiece into a PVC tube that splits into two paths. One path is connected to an open balloon valve. When the balloon is inflated and blocks the path, air is redirected into the other path which is gated by a one-way valve.

Recruiting Locations

University of Wisconsin - Madison
Madison, Wisconsin 53705
Contact:
Jack Jiang, MD
jjjiang@wisc.edu

More Details

NCT ID
NCT06975046
Status
Recruiting
Sponsor
University of Wisconsin, Madison

Study Contact

Jack Jiang, MD
608-265-7888
jjjiang@wisc.edu

Detailed Description

The primary goals of this research are to develop noninvasive aerodynamic assessments specific to the pediatric population, and to describe differences between healthy and dysphonic pediatric voices between the ages of 4-17 years. An adult cohort (ages 18-65) will function as a comparison group for incomplete interruption. To account for challenges associated with pediatric data collection, we will modify our current devices and methods of aerodynamic assessment to be better suited for use with the pediatric population and aim to increase measurement reliability in younger subjects. Our proposed modifications include shorter trial times, auditory masking, the use of cheek restraints, and gamification. After identification of optimal data collection conditions for each method, we will compare these in a large group of children with normal voice. These data will be compared to data from children with vocal fold nodules or polyp. All data will be compiled into a pediatric vocal health database.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.