Purpose

This clinical trial studies whether a patient navigation (PN) intervention can be used to improve risk management among women at high risk of breast cancer. Women with a family history of breast cancer have a higher lifetime risk of developing it. Risk management can benefit women at high risk of breast cancer and can include surveillance routines, preventative surgeries, and medications that can dramatically lower the risk of breast cancer and allow early detection. Although risk management can benefit women at high risk of breast cancer, only a small amount actually use it. PN is a healthcare service that is designed to guide a patient through the healthcare system and reduce barriers to timely screening, follow-up, diagnosis, treatment, and supportive care. The PN intervention in this study is designed to help give women the information and support they need to make choices about their breast cancer risk that they feel good about, which may improve risk management.

Condition

Eligibility

Eligible Ages
Between 18 Years and 75 Years
Eligible Sex
Female
Accepts Healthy Volunteers
Yes

Criteria

Inclusion Criteria:

- Are non-Hispanic Black or non-Hispanic white

- Identify as women

- Are between 18 and 75 years old

- Have been identified as at potentially high risk by a population-based risk
screening program

- Have never been diagnosed with breast or ovarian cancer

- Are early in their risk-management adoption process, defined as currently
identifying with stage 0 (never heard of it) or 1 (haven't decided) of the
risk-management adoption pathway (R-MAP) in relation to at least one of the four
risk-management actions recommended for all high-risk women: attending genetic
counseling appointment, having a personalized risk assessment, undergoing annual
clinical breast exams, and considering chemoprevention

- Who do not believe cancer can be prevented and/or have not received risk-management
guidance from a specialist

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Health Services Research
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Arm I (informational websites, PN)
Participants receive links to informational websites on breast cancer risk and risk management options on study. Participants also receive phone calls from a single patient navigator and discuss breast cancer risk and risk-management options once a month for 8 months. Participants may choose to receive additional patient navigator phone calls as needed on study.
  • Other: Educational Intervention
    Receive links to informational websites
    Other names:
    • Education for Intervention
    • Intervention by Education
    • Intervention through Education
    • Intervention, Educational
  • Behavioral: Patient Navigation
    Receive patient navigator phone calls
    Other names:
    • Patient Navigator Program
  • Other: Survey Administration
    Ancillary studies
  • Behavioral: Telephone-Based Intervention
    Receive patient navigator phone calls
Active Comparator
Arm II (informational websites)
Participants receive links to informational websites on breast cancer risk and risk management options on study.
  • Other: Educational Intervention
    Receive links to informational websites
    Other names:
    • Education for Intervention
    • Intervention by Education
    • Intervention through Education
    • Intervention, Educational
  • Other: Survey Administration
    Ancillary studies

Recruiting Locations

Ohio State University Comprehensive Cancer Center
Columbus, Ohio 43210
Contact:
Tasleem J. Padamsee, PhD
614-688-0986
padamsee.1@osu.edu

More Details

NCT ID
NCT06950008
Status
Recruiting
Sponsor
Ohio State University Comprehensive Cancer Center

Study Contact

The Ohio State University Comprehensive Cancer Center
800-293-5066
OSUCCCClinicaltrials@osumc.edu

Detailed Description

PRIMARY OBJECTIVE: I. Test the feasibility of the PN intervention and of recruiting participants to a randomized controlled trial of the intervention. OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants receive links to informational websites on breast cancer risk and risk management options on study. Participants also receive phone calls from a single patient navigator and discuss breast cancer risk and risk-management options once a month for 8 months. Participants may choose to receive additional patient navigator phone calls as needed on study. ARM II: Participants receive links to informational websites on breast cancer risk and risk management options on study. After completion of study intervention, participants are followed for up to 1 month.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.