Print Send My Information

Purpose

This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of the endotracheal tube during intubation of critically ill adults.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  1. Patient is located in a participating unit (ED or ICU) 2. Patient is undergoing tracheal intubation. 3. The clinician intends to use an exhaled CO2 detection device to confirm tracheal placement of the tube.

Exclusion Criteria

  1. Patient is known to be a prisoner 2. Patient is known to be < 18 years old 3. A responsible clinician has determined that sole use of either waveform capnography or colorimetric testing is required for optimal care of the patient.

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Critically ill adults undergoing emergency tracheal intubation Adult patients who are undergoing emergency intubation in the ED and ICU
  • Diagnostic Test: Colorimetric carbon dioxide (CO2) detection
    All patients will undergo colorimetric carbon dioxide (CO2) detection. The reading will be assessed by a clinician at the bedside who will answer yes or no to the following question, asked after 7 breaths have been delivered following intubation: "Is the color change consistent with a tube located in the trachea?"
  • Diagnostic Test: Waveform capnography
    All patients will undergo waveform capnography. The reading will be assessed by a clinician at the bedside who will answer yes or no to the following question, asked after 7 breaths have been delivered following intubation: " Is the waveform consistent with a tube located in the trachea?"

Recruiting Locations

Lahey Hospital & Medical Center
Burlington 4931737, Massachusetts 6254926 01805
Contact:
Avignat Patel, MD
781-744-5100
Avignat.S.Patel@lahey.org

Hennepin Healthcare
Minneapolis 5037649, Minnesota 5037779 55415
Contact:
Brian Driver
612-873-7448
brian.driver@hcmed.org

Wake Forest School of Medicine
Winston-Salem 4499612, North Carolina 4482348 27157
Contact:
John Gaillard, MD
336-758-5000
jgaillar@wakehealth.edu

The Ohio State University College of Medicine
Columbus 4509177, Ohio 5165418 43210
Contact:
Matthew Exline, MD
614-293-8000
Matthew.Exline@osumc.edu

Oregon Health and Sciences University
Portland 5746545, Oregon 5744337 97239
Contact:
Akram Khan, MBBS
503-494-8311
khana@ohsu.edu

More Details

NCT ID
NCT06934876
Status
Recruiting
Sponsor
Brian Driver

Study Contact

Brian Driver, MD
6128737448
brian.driver@hcmed.org

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.

For help using this page: trialstoday@researchmatch.org or call 855-514-7001

ResearchMatch is funded in part by the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program, led by the NIH’s National Center for Advancing Translational Sciences (NCATS), grants UL1TR000445 and 1U54RR032646-01, and grant U24TR001579 from NCATS and the National Library of Medicine. The content of this website is solely the responsibility of ResearchMatch and Vanderbilt University and does not necessarily represent the official views of the NIH, NCATS, or NLM.

Vanderbilt University Medical Center