Purpose

The purpose of this clinical trial is to determine the impact of a home-based pulmonary rehabilitation program with health coaching on patient-reported respiratory-related quality of life and physical activity, as compared to usual care in patients with fibrotic interstitial lung disease.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • F-ILD diagnosis, any disease subtype, active or prior medical treatment - >10% fibrosis on CT imaging - mMRC dyspnea score >1 - All racial or ethnic categories, including non-English speakers (professional translators will be engaged to support screening, enrollment, and study participation)

Exclusion Criteria

  • Inability to walk (orthopedic/neurologic/cardiac limitation causing immobility) - Cognitive impairment or inability to understand and follow instructions - Traditional center-based PR completed within 3 months of initial study recruitment - Transition to hospice or end-of-life care at the time of screening - Acute exacerbation at the time of screening

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Intervention Model Description
Randomized waitlist control
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Home-based Pulmonary Rehabilitation with Health Coaching Group
Twelve-week intervention with home-based pulmonary rehabilitation and health coaching.
  • Behavioral: Home-based Pulmonary Rehab
    Participants are expected to engage in the home-based PR routine five to six days a week for the entire 12-week study period. The PR routine begins with slow upper body and timed breathing exercises, followed by two slow balance walks for 6 minutes each. The total exercise time is 24 minutes a day followed by a 4-minute mindful breathing meditation/cool down. Exercises may be modified or repeated according to baseline activity level and as conditioning improves.
No Intervention
Non-use Waitlist Control Observation Group
12-week non-use usual care waitlist with transition to intervention group at the end of the observation period.

Recruiting Locations

Mayo Clinic in Arizona
Scottsdale 5313457, Arizona 5551752 85259

Mayo Clinic in Florida
Jacksonville 4160021, Florida 4155751 32224

Mayo Clinic in Rochester
Rochester 5043473, Minnesota 5037779 55905
Contact:
Johanna Hoult, MS
507-293-1989
hoult.johanna@mayo.edu

More Details

NCT ID
NCT06751069
Status
Recruiting
Sponsor
Mayo Clinic

Study Contact

Johanna Hoult, MS
507-293-1989
hoult.johanna@mayo.edu

Detailed Description

The fibrotic interstitial lung diseases (f-ILD) are a group of progressive and debilitating lung diseases sharing characteristics of lung scarring on imaging and restricted breathing on pulmonary function testing (PFT). Symptoms include shortness of breath, cough, and fatigue, eventually leading to deconditioning and poor quality of life. While medical therapies are available for slowing or stopping the loss of lung function, only pulmonary rehabilitation (PR) has shown a positive impact on patient-reported shortness of breath and physical activity. Unfortunately, PR may not be widely available to all patients, and some patients may become too ill to participate in traditional center-based programs. A primary hypothesis is that modifying the content, delivery, and setting for PR in patients with f-ILD to improve access or ease of use and supporting behavior change through a health coach will have a measurable and sustained positive impact on patient well-being and quality of life as compared to no participation or non-use.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.