Purpose

This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Criteria

Inclusion Criteria:

1. ≥ 18 years old at the time of informed consent

2. Written informed consent and HIPAA authorization for release of personal health
information.

3. Active SCLC diagnosis.

Study Design

Phase
Study Type
Observational
Observational Model
Case-Only
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Active SCLC Diagnosis
  • Procedure: Biospecimen Collection
    Lung, liver, skin, subcutaneous metastases, and blood specimens may be collected via rapid autopsy within 10 hours of expiration.

Recruiting Locations

Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana 46202
Contact:
Gabby Kline, BA
317-278-2514
gabkline@iu.edu

Roudebush VA Medical Center
Indianapolis, Indiana 46202
Contact:
Cynthia Johnson
317-278-7403
cydjohns@iu.edu

Sidney and Lois Eskenazi Hospital
Indianapolis, Indiana 46202
Contact:
Gaby Kline, BA
317-278-2514
gabkline@iu.edu

More Details

NCT ID
NCT05889546
Status
Recruiting
Sponsor
Indiana University

Study Contact

Gabby Kline, BA
(317) 278-2514
gabkline@iu.edu

Detailed Description

The goal of this project to establish a rapid autopsy program in SCLC at the IUSCCC and outline the key components necessary for tumor tissue acquisition. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, and the IUSCCC Translational Research Core. Tumor tissue collected will be used for protein and gene analysis and RNA, whole exome sequencing in addition to the establishment of SCLC. This research is part of a discovery project in which biological and molecular markers of SCLC will be identified.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.