Serious Game-based Interventions in Patients With Mild Cognitive Impairment Outside the Clinic
Purpose
This study will evaluate the therapeutic efficacy of Neuro-World cognitive training games (Woorisoft, S. Korea) in patients with mild cognitive impairment.
Condition
- Mild Cognitive Impairment
Eligibility
- Eligible Ages
- Over 55 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Seventeen points or greater and smaller than twenty-six points on the Montreal Cognitive Assessment (MoCA) - Fifty-five years old and above - Minimal technological literacy (i.e. ability to use a tablet independently) - Having a computer for online videoconferencing-based communication (necessary for online cognitive assessments)
Exclusion Criteria
- Confounding neurological and psychiatric disorders - History of traumatic brain injury - Clinically known hearing or vision impairment - Severe upper-limb motor impairments that could impact the use of mobile devices - Clinical presentations suggestive of dementia with Lewy bodies, progressive supranuclear palsy, multiple system atrophy, or vascular parkinsonism - Diagnosis of dementia - Major depression - Any significant upper-limb impairment that could affect tablet use - Participation in any other therapist-supervised cognitive training
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover Assignment
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Game Intervention |
Study participants play Neuro-World 30 minutes per day, twice a week for 12 weeks in your home settings (24 times). |
|
|
No Intervention No Intervention |
Study participants do not engage in any cognitive training. |
|
Recruiting Locations
Amherst, Massachusetts 01003
Newark, New Jersey 07102
More Details
- NCT ID
- NCT04920123
- Status
- Recruiting
- Sponsor
- University of Massachusetts, Amherst
Detailed Description
This study will be a cross-over randomized controlled trial. Fifty participants will be enrolled and randomly assigned to group A or group B. Group A will self-administer Neuro-World cognitive training games for 30 minutes a day, twice a week for 12 weeks in the home setting (i.e., intervention period). For the following 12 weeks, the participants will not engage in any therapist-supervised cognitive therapies (i.e., no-intervention period). Group B will not engage in any therapist-supervised cognitive therapies (i.e., no-intervention period). For the following 12 weeks, the participants will self-administer Neuro-World cognitive training games for 30 minutes a day, twice a week in the home setting (i.e., intervention period). All the participants in both groups will receive phone calls twice a week to 1) provide feedback on their adherence to Neuro-World cognitive training (during the intervention period) and 2) learn any significant changes in the level of their daily activities (during the no-intervention period and the intervention period).