Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
Purpose
This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.
Conditions
- Colorectal Cancer
- Sarcopenia
Eligibility
- Eligible Ages
- Over 60 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Newly diagnosed metastatic CRC or newly recognized metastatic recurrence of CRC >= to 3 months (12 weeks) from completion of treatment of non-metastatic CRC. - Planning to or recently started to undergo undergo immunotherapy and/or 5-FU based chemotherapy as a first line of treatment. 5-FU chemotherapy can be 5-FU alone or in combination with oxaliplatin and/or irinotecan +/- immunotherapy. Capecitabine is also acceptable. - Estimated life expectancy >= 6 months. - Patients must be able to comprehend English or Spanish (for questionnaire completion). - Ability to understand and the willingness to sign a written informed consent document. - Patient eligibility is not dependent on BMI or weight. Patients with a significant (+- > 10%) body weight change in the previous 12 months are eligible for this study.
Exclusion Criteria
- Patients enrolled on hospice. - Prior systemic chemotherapy for metastatic colorectal cancer (ok if adjuvant chemotherapy completed >= 3 months (12 weeks) prior to this disease disease recurrence and treatment). - Patients may not be receiving any other investigational agents. - No untreated brain metastases. Patients with treated brain metastases are eligible. - Patients on or planned to undergo radiation therapy in near future.
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| Adults 60-74 years | ||
| Adults >= 75 years |
Recruiting Locations
Beebe South Coastal Health Campus
Millville 4143696, Delaware 4142224 19967
Millville 4143696, Delaware 4142224 19967
Helen F Graham Cancer Center
Newark 4143861, Delaware 4142224 19713
Newark 4143861, Delaware 4142224 19713
Medical Oncology Hematology Consultants PA
Newark 4143861, Delaware 4142224 19713
Newark 4143861, Delaware 4142224 19713
Beebe Health Campus
Rehoboth Beach 4144284, Delaware 4142224 19971
Rehoboth Beach 4144284, Delaware 4142224 19971
Christiana Care Health System-Wilmington Hospital
Wilmington 4145381, Delaware 4142224 19801
Wilmington 4145381, Delaware 4142224 19801
MedStar Georgetown University Hospital
Washington D.C. 4140963, District of Columbia 4138106 20007
Washington D.C. 4140963, District of Columbia 4138106 20007
Contact:
Site Public Contact
202-444-2223
Site Public Contact
202-444-2223
John B Amos Cancer Center
Columbus 4188985, Georgia 4197000 31904
Columbus 4188985, Georgia 4197000 31904
Illinois CancerCare-Bloomington
Bloomington 4885164, Illinois 4896861 61704
Bloomington 4885164, Illinois 4896861 61704
Illinois CancerCare-Canton
Canton 4831990, Illinois 4896861 61520
Canton 4831990, Illinois 4896861 61520
SIH Cancer Institute
Carterville 4235311, Illinois 4896861 62918
Carterville 4235311, Illinois 4896861 62918
John H Stroger Jr Hospital of Cook County
Chicago 4887398, Illinois 4896861 60612
Chicago 4887398, Illinois 4896861 60612
Contact:
Site Public Contact
312-864-5204
Site Public Contact
312-864-5204
Carle at The Riverfront
Danville 4889426, Illinois 4896861 61832
Danville 4889426, Illinois 4896861 61832
Cancer Care Specialists of Illinois - Decatur
Decatur 4236895, Illinois 4896861 62526
Decatur 4236895, Illinois 4896861 62526
Crossroads Cancer Center
Effingham 4237727, Illinois 4896861 62401
Effingham 4237727, Illinois 4896861 62401
Illinois CancerCare-Galesburg
Galesburg 4893392, Illinois 4896861 61401
Galesburg 4893392, Illinois 4896861 61401
Carle Physician Group - Mattoon/Charleston
Mattoon 4244099, Illinois 4896861 61938
Mattoon 4244099, Illinois 4896861 61938
SSM Health Good Samaritan
Mount Vernon 4245152, Illinois 4896861 62864
Mount Vernon 4245152, Illinois 4896861 62864
Contact:
Site Public Contact
618-242-4600
Site Public Contact
618-242-4600
Carle BroMenn Medical Center
Normal 4903780, Illinois 4896861 61761
Normal 4903780, Illinois 4896861 61761
Carle Cancer Institute Normal
Normal 4903780, Illinois 4896861 61761
Normal 4903780, Illinois 4896861 61761
Cancer Care Center of O'Fallon
O'Fallon 4245926, Illinois 4896861 62269
O'Fallon 4245926, Illinois 4896861 62269
Illinois CancerCare-Ottawa Clinic
Ottawa 4905006, Illinois 4896861 61350
Ottawa 4905006, Illinois 4896861 61350
Illinois CancerCare-Pekin
Pekin 4905599, Illinois 4896861 61554
Pekin 4905599, Illinois 4896861 61554
Illinois CancerCare-Peoria
Peoria 4905687, Illinois 4896861 61615
Peoria 4905687, Illinois 4896861 61615
Illinois CancerCare-Peru
Peru 4905770, Illinois 4896861 61354
Peru 4905770, Illinois 4896861 61354
Southern Illinois University School of Medicine
Springfield 4250542, Illinois 4896861 62702
Springfield 4250542, Illinois 4896861 62702
Contact:
Site Public Contact
217-545-7929
Site Public Contact
217-545-7929
Springfield Clinic
Springfield 4250542, Illinois 4896861 62702
Springfield 4250542, Illinois 4896861 62702
Contact:
Site Public Contact
800-444-7541
Site Public Contact
800-444-7541
Carle Cancer Center
Urbana 4914570, Illinois 4896861 61801
Urbana 4914570, Illinois 4896861 61801
Illinois CancerCare - Washington
Washington 4915545, Illinois 4896861 61571
Washington 4915545, Illinois 4896861 61571
The University of Iowa - Ankeny
Ankeny 4846960, Iowa 4862182 50023
Ankeny 4846960, Iowa 4862182 50023
Contact:
515-282-2921
515-282-2921
Saint Anthony Regional Hospital
Carroll 4850478, Iowa 4862182 51401
Carroll 4850478, Iowa 4862182 51401
Physicians' Clinic of Iowa PC
Cedar Rapids 4850751, Iowa 4862182 52402
Cedar Rapids 4850751, Iowa 4862182 52402
Contact:
319-297-2900
319-297-2900
Oncology Associates at Mercy Medical Center
Cedar Rapids 4850751, Iowa 4862182 52403
Cedar Rapids 4850751, Iowa 4862182 52403
Contact:
Site Public Contact
319-363-2690
Site Public Contact
319-363-2690
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive 4852065, Iowa 4862182 50325
Clive 4852065, Iowa 4862182 50325
Contact:
515-241-3305
515-241-3305
Iowa Methodist Medical Center
Des Moines 4853828, Iowa 4862182 50309
Des Moines 4853828, Iowa 4862182 50309
Contact:
515-241-6727
515-241-6727
The University of Iowa-Des Moines
Des Moines 4853828, Iowa 4862182 50309
Des Moines 4853828, Iowa 4862182 50309
Contact:
Site Public Contact
515-282-2921
Site Public Contact
515-282-2921
Broadlawns Medical Center
Des Moines 4853828, Iowa 4862182 50314
Des Moines 4853828, Iowa 4862182 50314
Contact:
515-282-2200
515-282-2200
Mercy Medical Center - Des Moines
Des Moines 4853828, Iowa 4862182 50314
Des Moines 4853828, Iowa 4862182 50314
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines 4853828, Iowa 4862182 50314
Des Moines 4853828, Iowa 4862182 50314
Contact:
515-241-3305
515-241-3305
UI Healthcare Mission Cancer and Blood - Fort Dodge
Fort Dodge 4857486, Iowa 4862182 50501
Fort Dodge 4857486, Iowa 4862182 50501
Louisiana Hematology Oncology Associates LLC
Baton Rouge 4315588, Louisiana 4331987 70809
Baton Rouge 4315588, Louisiana 4331987 70809
Mary Bird Perkins Cancer Center
Baton Rouge 4315588, Louisiana 4331987 70809
Baton Rouge 4315588, Louisiana 4331987 70809
MBP Cancer Center - Baton Rouge General
Baton Rouge 4315588, Louisiana 4331987 70809
Baton Rouge 4315588, Louisiana 4331987 70809
Terrebonne General Medical Center
Houma 4328010, Louisiana 4331987 70360
Houma 4328010, Louisiana 4331987 70360
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor 4984247, Michigan 5001836 48106
Ann Arbor 4984247, Michigan 5001836 48106
Trinity Health IHA Medical Group Hematology Oncology-Brighton
Brighton 4986994, Michigan 5001836 48114
Brighton 4986994, Michigan 5001836 48114
Trinity Health Medical Center-Brighton
Brighton 4986994, Michigan 5001836 48114
Brighton 4986994, Michigan 5001836 48114
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton 4987990, Michigan 5001836 48188
Canton 4987990, Michigan 5001836 48188
Trinity Health Medical Center - Canton
Canton 4987990, Michigan 5001836 48188
Canton 4987990, Michigan 5001836 48188
Chelsea Hospital
Chelsea 4988628, Michigan 5001836 48118
Chelsea 4988628, Michigan 5001836 48118
Trinity Health IHA Hematology Oncology Consultants-Chelsea Hospital
Chelsea 4988628, Michigan 5001836 48118
Chelsea 4988628, Michigan 5001836 48118
Cancer Hematology Centers - Flint
Flint 4992982, Michigan 5001836 48503
Flint 4992982, Michigan 5001836 48503
Genesee Hematology Oncology PC
Flint 4992982, Michigan 5001836 48503
Flint 4992982, Michigan 5001836 48503
Genesys Hurley Cancer Institute
Flint 4992982, Michigan 5001836 48503
Flint 4992982, Michigan 5001836 48503
Marshfield Medical Center Dickinson
Iron Mountain 4997232, Michigan 5001836 49801
Iron Mountain 4997232, Michigan 5001836 49801
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia 4999837, Michigan 5001836 48154
Livonia 4999837, Michigan 5001836 48154
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac 5006166, Michigan 5001836 48341
Pontiac 5006166, Michigan 5001836 48341
Corewell Health Reed City Hospital
Reed City 5006946, Michigan 5001836 49677
Reed City 5006946, Michigan 5001836 49677
University of Michigan Health - West
Wyoming 5015618, Michigan 5001836 49519
Wyoming 5015618, Michigan 5001836 49519
Trinity Health IHA Medical Group Hematology Oncology -Ann Arbor
Ypsilanti 5015688, Michigan 5001836 48197
Ypsilanti 5015688, Michigan 5001836 48197
Sanford Joe Lueken Cancer Center
Bemidji 5017822, Minnesota 5037779 56601
Bemidji 5017822, Minnesota 5037779 56601
Essentia Health Saint Joseph's Medical Center
Brainerd 5019116, Minnesota 5037779 56401
Brainerd 5019116, Minnesota 5037779 56401
Mercy Hospital
Coon Rapids 5022025, Minnesota 5037779 55433
Coon Rapids 5022025, Minnesota 5037779 55433
Essentia Health - Deer River Clinic
Deer River 5024099, Minnesota 5037779 56636
Deer River 5024099, Minnesota 5037779 56636
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes 5024237, Minnesota 5037779 56501
Detroit Lakes 5024237, Minnesota 5037779 56501
Essentia Health Cancer Center
Duluth 5024719, Minnesota 5037779 55805
Duluth 5024719, Minnesota 5037779 55805
Fairview Southdale Hospital
Edina 5025264, Minnesota 5037779 55435
Edina 5025264, Minnesota 5037779 55435
Essentia Health Hibbing Clinic
Hibbing 5030005, Minnesota 5037779 55746
Hibbing 5030005, Minnesota 5037779 55746
Contact:
218-786-3308
218-786-3308
Minnesota Oncology Hematology PA-Maplewood
Maplewood 5036588, Minnesota 5037779 55109
Maplewood 5036588, Minnesota 5037779 55109
Saint John's Hospital - Healtheast
Maplewood 5036588, Minnesota 5037779 55109
Maplewood 5036588, Minnesota 5037779 55109
Abbott-Northwestern Hospital
Minneapolis 5037649, Minnesota 5037779 55407
Minneapolis 5037649, Minnesota 5037779 55407
New Ulm Medical Center
New Ulm 5039173, Minnesota 5037779 56073
New Ulm 5039173, Minnesota 5037779 56073
Essentia Health - Park Rapids
Park Rapids 5040822, Minnesota 5037779 56470
Park Rapids 5040822, Minnesota 5037779 56470
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park 5045021, Minnesota 5037779 55416
Saint Louis Park 5045021, Minnesota 5037779 55416
Regions Hospital
Saint Paul 5045360, Minnesota 5037779 55101
Saint Paul 5045360, Minnesota 5037779 55101
United Hospital
Saint Paul 5045360, Minnesota 5037779 55102
Saint Paul 5045360, Minnesota 5037779 55102
Essentia Health Sandstone
Sandstone 5045908, Minnesota 5037779 55072
Sandstone 5045908, Minnesota 5037779 55072
Saint Francis Regional Medical Center
Shakopee 5046997, Minnesota 5037779 55379
Shakopee 5046997, Minnesota 5037779 55379
Essentia Health Virginia Clinic
Virginia 5051468, Minnesota 5037779 55792
Virginia 5051468, Minnesota 5037779 55792
Rice Memorial Hospital
Willmar 5052916, Minnesota 5037779 56201
Willmar 5052916, Minnesota 5037779 56201
Saint Francis Medical Center
Cape Girardeau 4379966, Missouri 4398678 63703
Cape Girardeau 4379966, Missouri 4398678 63703
Parkland Health Center - Farmington
Farmington 4386289, Missouri 4398678 63640
Farmington 4386289, Missouri 4398678 63640
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Heartland Regional Medical Center
Saint Joseph 4407010, Missouri 4398678 64506
Saint Joseph 4407010, Missouri 4398678 64506
Sainte Genevieve County Memorial Hospital
Sainte Genevieve 4407294, Missouri 4398678 63670
Sainte Genevieve 4407294, Missouri 4398678 63670
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Mercy Hospital Springfield
Springfield 4409896, Missouri 4398678 65804
Springfield 4409896, Missouri 4398678 65804
Contact:
Site Public Contact
417-269-4520
Site Public Contact
417-269-4520
CoxHealth South Hospital
Springfield 4409896, Missouri 4398678 65807
Springfield 4409896, Missouri 4398678 65807
Contact:
417-269-4520
417-269-4520
Missouri Baptist Medical Center
St Louis 4407066, Missouri 4398678 63131
St Louis 4407066, Missouri 4398678 63131
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Missouri Baptist Sullivan Hospital
Sullivan 4410669, Missouri 4398678 63080
Sullivan 4410669, Missouri 4398678 63080
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
BJC Outpatient Center at Sunset Hills
Sunset Hills 4410836, Missouri 4398678 63127
Sunset Hills 4410836, Missouri 4398678 63127
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Carolinas Medical Center/Levine Cancer Institute
Charlotte 4460243, North Carolina 4482348 28203
Charlotte 4460243, North Carolina 4482348 28203
Contact:
800-804-9376
800-804-9376
Atrium Health Pineville/LCI-Pineville
Charlotte 4460243, North Carolina 4482348 28210
Charlotte 4460243, North Carolina 4482348 28210
Contact:
980-442-2000
980-442-2000
Levine Cancer Institute-SouthPark
Charlotte 4460243, North Carolina 4482348 28211
Charlotte 4460243, North Carolina 4482348 28211
Contact:
980-442-2000
980-442-2000
Atrium Health University City/LCI-University
Charlotte 4460243, North Carolina 4482348 28262
Charlotte 4460243, North Carolina 4482348 28262
Contact:
800-804-9376
800-804-9376
Wake Forest University at Clemmons
Clemmons 4461015, North Carolina 4482348 27012
Clemmons 4461015, North Carolina 4482348 27012
Contact:
Site Public Contact
888-716-9259
Site Public Contact
888-716-9259
Atrium Health Cabarrus/LCI-Concord
Concord 4461574, North Carolina 4482348 28025
Concord 4461574, North Carolina 4482348 28025
Contact:
800-804-9376
800-804-9376
Levine Cancer Institute-Gaston
Gastonia 4467732, North Carolina 4482348 28054
Gastonia 4467732, North Carolina 4482348 28054
Contact:
800-804-9376
800-804-9376
Wake Forest Baptist Health - Wilkes Medical Center
Wilkesboro 4499138, North Carolina 4482348 28659
Wilkesboro 4499138, North Carolina 4482348 28659
Contact:
888-716-9253
888-716-9253
Wake Forest University Health Sciences
Winston-Salem 4499612, North Carolina 4482348 27157
Winston-Salem 4499612, North Carolina 4482348 27157
Contact:
Site Public Contact
336-713-6771
Site Public Contact
336-713-6771
Sanford Bismarck Medical Center
Bismarck 5688025, North Dakota 5690763 58501
Bismarck 5688025, North Dakota 5690763 58501
Essentia Health Cancer Center-South University Clinic
Fargo 5059163, North Dakota 5690763 58103
Fargo 5059163, North Dakota 5690763 58103
Sanford Broadway Medical Center
Fargo 5059163, North Dakota 5690763 58122
Fargo 5059163, North Dakota 5690763 58122
Sanford Roger Maris Cancer Center
Fargo 5059163, North Dakota 5690763 58122
Fargo 5059163, North Dakota 5690763 58122
Adena Regional Medical Center
Chillicothe 4828890, Ohio 5165418 45601
Chillicothe 4828890, Ohio 5165418 45601
The Mark H Zangmeister Center
Columbus 4509177, Ohio 5165418 43219
Columbus 4509177, Ohio 5165418 43219
Armes Family Cancer Center
Findlay 5153924, Ohio 5165418 45840
Findlay 5153924, Ohio 5165418 45840
Knox Community Hospital
Mount Vernon 5163799, Ohio 5165418 43050
Mount Vernon 5163799, Ohio 5165418 43050
Licking Memorial Hospital
Newark 5164466, Ohio 5165418 43055
Newark 5164466, Ohio 5165418 43055
Southern Ohio Medical Center
Portsmouth 4521816, Ohio 5165418 45662
Portsmouth 4521816, Ohio 5165418 45662
Springfield Regional Cancer Center
Springfield 4525353, Ohio 5165418 45504
Springfield 4525353, Ohio 5165418 45504
Genesis Healthcare System Cancer Care Center
Zanesville 4528923, Ohio 5165418 43701
Zanesville 4528923, Ohio 5165418 43701
Geisinger Medical Center
Danville 5186327, Pennsylvania 6254927 17822
Danville 5186327, Pennsylvania 6254927 17822
Geisinger Medical Center-Cancer Center Hazleton
Hazleton 5193011, Pennsylvania 6254927 18201
Hazleton 5193011, Pennsylvania 6254927 18201
Geisinger Medical Oncology-Lewisburg
Lewisburg 5197842, Pennsylvania 6254927 17837
Lewisburg 5197842, Pennsylvania 6254927 17837
Lewistown Hospital
Lewistown 5197850, Pennsylvania 6254927 17044
Lewistown 5197850, Pennsylvania 6254927 17044
Geisinger Cancer Services-Pottsville
Pottsville 5207080, Pennsylvania 6254927 17901
Pottsville 5207080, Pennsylvania 6254927 17901
Community Medical Center
Scranton 5211303, Pennsylvania 6254927 18510
Scranton 5211303, Pennsylvania 6254927 18510
Geisinger Medical Oncology-Selinsgrove
Selinsgrove 5211411, Pennsylvania 6254927 17870
Selinsgrove 5211411, Pennsylvania 6254927 17870
Geisinger Medical Group
State College 5213681, Pennsylvania 6254927 16801
State College 5213681, Pennsylvania 6254927 16801
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre 5219488, Pennsylvania 6254927 18711
Wilkes-Barre 5219488, Pennsylvania 6254927 18711
Prisma Health Cancer Institute - Spartanburg
Boiling Springs 4571805, South Carolina 4597040 29316
Boiling Springs 4571805, South Carolina 4597040 29316
Contact:
Site Public Contact
864-241-6251
Site Public Contact
864-241-6251
Prisma Health Cancer Institute - Easley
Easley 4577263, South Carolina 4597040 29640
Easley 4577263, South Carolina 4597040 29640
Gibbs Cancer Center-Gaffney
Gaffney 4579418, South Carolina 4597040 29341
Gaffney 4579418, South Carolina 4597040 29341
Prisma Health Cancer Institute - Butternut
Greenville 4580543, South Carolina 4597040 29605
Greenville 4580543, South Carolina 4597040 29605
Contact:
Site Public Contact
864-241-6251
Site Public Contact
864-241-6251
Prisma Health Cancer Institute - Faris
Greenville 4580543, South Carolina 4597040 29605
Greenville 4580543, South Carolina 4597040 29605
Contact:
Site Public Contact
864-241-6251
Site Public Contact
864-241-6251
Prisma Health Cancer Institute - Eastside
Greenville 4580543, South Carolina 4597040 29615
Greenville 4580543, South Carolina 4597040 29615
Contact:
Site Public Contact
864-241-6251
Site Public Contact
864-241-6251
Prisma Health Cancer Institute - Greer
Greer 4580599, South Carolina 4597040 29650
Greer 4580599, South Carolina 4597040 29650
Contact:
Site Public Contact
864-241-6251
Site Public Contact
864-241-6251
Gibbs Cancer Center-Pelham
Greer 4580599, South Carolina 4597040 29651
Greer 4580599, South Carolina 4597040 29651
Prisma Health Cancer Institute - Seneca
Seneca 4595346, South Carolina 4597040 29672
Seneca 4595346, South Carolina 4597040 29672
Contact:
Site Public Contact
864-241-6251
Site Public Contact
864-241-6251
Spartanburg Medical Center
Spartanburg 4597200, South Carolina 4597040 29303
Spartanburg 4597200, South Carolina 4597040 29303
MGC Hematology Oncology-Union
Union 4599214, South Carolina 4597040 29379
Union 4599214, South Carolina 4597040 29379
Sanford Cancer Center Oncology Clinic
Sioux Falls 5231851, South Dakota 5769223 57104
Sioux Falls 5231851, South Dakota 5769223 57104
Sanford USD Medical Center - Sioux Falls
Sioux Falls 5231851, South Dakota 5769223 57117-5134
Sioux Falls 5231851, South Dakota 5769223 57117-5134
Duluth Clinic Ashland
Ashland 5244247, Wisconsin 5279468 54806
Ashland 5244247, Wisconsin 5279468 54806
Marshfield Medical Center-EC Cancer Center
Eau Claire 5251436, Wisconsin 5279468 54701
Eau Claire 5251436, Wisconsin 5279468 54701
Saint Vincent Hospital Cancer Center Green Bay
Green Bay 5254962, Wisconsin 5279468 54301
Green Bay 5254962, Wisconsin 5279468 54301
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay 5254962, Wisconsin 5279468 54303
Green Bay 5254962, Wisconsin 5279468 54303
Marshfield Medical Center-Marshfield
Marshfield 5261969, Wisconsin 5279468 54449
Marshfield 5261969, Wisconsin 5279468 54449
Marshfield Medical Center - Minocqua
Minocqua 5263156, Wisconsin 5279468 54548
Minocqua 5263156, Wisconsin 5279468 54548
Marshfield Medical Center-Rice Lake
Rice Lake 5268798, Wisconsin 5279468 54868
Rice Lake 5268798, Wisconsin 5279468 54868
Essentia Health-Spooner Clinic
Spooner 5274034, Wisconsin 5279468 54801
Spooner 5274034, Wisconsin 5279468 54801
Marshfield Medical Center-River Region at Stevens Point
Stevens Point 5274644, Wisconsin 5279468 54482
Stevens Point 5274644, Wisconsin 5279468 54482
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay 5274867, Wisconsin 5279468 54235-1495
Sturgeon Bay 5274867, Wisconsin 5279468 54235-1495
Marshfield Medical Center - Weston
Weston 5278693, Wisconsin 5279468 54476
Weston 5278693, Wisconsin 5279468 54476
More Details
- NCT ID
- NCT03998202
- Status
- Recruiting
- Sponsor
- Wake Forest University Health Sciences
Detailed Description
This is a prospective cohort study that examines the impact of myopenia on chemotherapy toxicity in overall survival (OS) in older adults with newly diagnosed metastatic colorectal cancer (CRC) receiving 5-Fluouracil (5FU)systemic chemotherapy. The study also explores the mediating influence of genetic variation in the association between myopenia and chemotherapy toxicity.