Smoking Cessation Behavioral Treatment Study
Purpose
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.
Condition
- Tobacco Use Disorder
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Age 18 and up - English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks - Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks - Current nicotine dependent smoker with a minimum smoking history of 2 years - Interest in quitting smoking
Exclusion Criteria
- Use of psychotropic (e.g. antiepileptic) medications in the past month - Positive urine drug screen - Presence of an untreated medical illness - Current or past psychosis - History of major neurological illness or head injury resulting in loss of consciousness - And contraindication to MRI, including claustrophobia - Among females, positive urine pregnancy test - Inability or unwillingness of subject to give informed consent
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Outcomes Assessor)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental MORE |
|
|
|
Active Comparator CBT |
|
Recruiting Locations
University of Missouri - Columbia
Columbia, Missouri 65211
Columbia, Missouri 65211
More Details
- NCT ID
- NCT03948893
- Status
- Recruiting
- Sponsor
- University of Missouri-Columbia