Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

Purpose

This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.

Condition

  • Alzheimers Disease

Eligibility

Eligible Ages
Between 50 Years and 90 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Report of objective or subjective memory concerns (by the participant and/or their informant) within the last year with or without a previous clinical diagnosis of MCI or dementia due to AD.

Exclusion Criteria

  • Dependency in basic activities of daily living (bADLs) due to cognitive impairment - Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted) - Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD - History of severe, clinically significant central nervous system trauma - Any serious medical condition that precludes a participant's safe participation and completion of a clinical study

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Screening
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Other
Screening Arm 		Participants will be assessed for their concentration of pTau217 in blood and cognitive score in the International Shopping List Test (ISLT).
  • Other: No Intervention
    Participants will have their blood drawn and cognitive score measured by the ISLT.

Recruiting Locations

Banner Alzheimer?s Institute
Phoenix, Arizona 85006

Banner Sun Health Research Institute
Sun City, Arizona 85351

Sun Valley Research Center, Inc.
Imperial, California 92251

Inglewood Clinicals
Inglewood, California 90301

Irvine Center for Clinical Research
Irvine, California 92614

Healthy Brain Clinic
Long Beach, California 90804

Oakland Clinical
Oakland, California 94609

Riverside Clinical
Riverside, California 92506

Syrentis Clinical Research
Santa Ana, California 92705

Cenexel California Neuroscience Research, LLC
Sherman Oaks, California 91403

Yale University
New Haven, Connecticut 06510

JEM Research LLC
Atlantis, Florida 33462

K2 Medical Research-Winter Garden
Clermont, Florida 34711

K2 Medical Research - The Villages
Lady Lake, Florida 32159

K2 Medical Research, LLC
Maitland, Florida 32751

Visionary Investigators Network- Neurology Aventura
Miami, Florida 33133

Renstar Medical Research
Ocala, Florida 34470

Charter Research - Winter Park/Orlando
Orlando, Florida 32803

Conquest Research - Lake Nona
Orlando, Florida 32832

Alzheimer's Research and Treatment Center
Stuart, Florida 34997

Axiom Brain Health LLC
Tampa, Florida 34654

Charter Research - Lady Lake/The Villages
The Villages, Florida 32162

Alzheimer?s Research and Treatment Center
Wellington, Florida 33414

Conquest Research, LLC
Winter Park, Florida 32789

Grady Memorial Hospital
Atlanta, Georgia 30303

Alzheimer's Research and Treatment Center - Columbus
Columbus, Georgia 31904

Accel Research Sites-NeuroStudies
Decatur, Georgia 30030

CenExel iResearch, LLC
Decatur, Georgia 30030

Center for Advanced Research & Education
Gainesville, Georgia 30501

Hawaii Pacific Neuroscience
Honolulu, Hawaii 96817

RE:Cognition (Chicago)
Chicago, Illinois 60611

Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville
Chicago, Illinois 60640

Tandem Clinical Research, LLC
Marrero, Louisiana 70072

Adams Clinical Boston
Boston, Massachusetts 02116

Boston Center for Memory
Newton, Massachusetts 02459

Adams Clinical Watertown
Watertown, Massachusetts 02472

Quest Research Institute
Farmington Hills, Michigan 48334

Washington University School of MedicineClinical Translational Research Unit
St Louis, Missouri 63110

The Cognitive and Research Center of New Jersey
Ridgewood, New Jersey 07450

The Cognitive and Research Center of New Jersey
Springfield, New Jersey 07081

IMA Clinical Research - Albuquerque
Albuquerque, New Mexico 87109

Basil Clinical
Laurelton, New York 11413-2016

Weill Cornell Medical College
New York, New York 10021

Adams Clinical Harlem
New York, New York 10029

AD-CARE, University of Rochester Medical Center
Rochester, New York 14620

Adams Clinical Bronx
The Bronx, New York 10461

Triad Clinical Trials
Greensboro, North Carolina 27410

Ohio State University
Columbus, Ohio 43221

Summit Research Network Inc.
Portland, Oregon 97210

Flourish Research ? Philadelphia
Plymouth Meeting, Pennsylvania 19462

Butler Hospital
Providence, Rhode Island 02906

Ralph H. Johnson VA Medical Center
Charleston, South Carolina 29403

Palmetto Clinical Trials
Summerville, South Carolina 29485

Genesis Neuroscience Clinic
Knoxville, Tennessee 37909

K2 Medical Research - Nashville
Nashville, Tennessee 37204

Gadolin Research, LLC
Beaumont, Texas 77702

South Texas Research Institute - Brownsville
Brownsville, Texas 78520

Kerwin Medical Center
Dallas, Texas 75216

Kerwin Research Center, LLC
Dallas, Texas 75231

South Texas Research Institute - Edinburg
Edinburg, Texas 78539

Re:Cognition Health - Fort Worth
Fort Worth, Texas 76104

Re:Cognition Health - Houston
Houston, Texas 77030

Mt.Olympus Medical Research
Katy, Texas 77450

El Faro Health and Therapeutics
Rio Grande City, Texas 78582

Sana Research, LLC
Arlington, Virginia 22205

Re:Cognition Health
Fairfax, Virginia 22031

National Clinical Research Inc.-Richmond
Richmond, Virginia 23294

University of Puerto Rico - Medical Science Campus
San Juan, Puerto Rico 00935

More Details

NCT ID
NCT07177352
Status
Recruiting
Sponsor
Hoffmann-La Roche

Study Contact

Reference Study ID Number: WP45722 https://forpatients.roche.com/
888-662-6728 (U.S. and Canada)
global-roche-genentech-trials@gene.com

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ResearchMatch is funded in part by the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program, led by the NIH’s National Center for Advancing Translational Sciences (NCATS), grants UL1TR000445 and 1U54RR032646-01, and grant U24TR001579 from NCATS and the National Library of Medicine. The content of this website is solely the responsibility of ResearchMatch and Vanderbilt University and does not necessarily represent the official views of the NIH, NCATS, or NLM.

Vanderbilt University Medical Center