The Advancing Dynamic And Personalized Training Study

Purpose

This study aims to enhance the Healthy Minds Program (HMP) app by developing and testing a personalized, data-driven approach to optimize long-term well-being. 1100 participants will be enrolled and on study for up to 4 months (4 week intervention plus 3 month follow-up).

Condition

  • Well-Being, Psychological

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Elevated symptoms of depression (PHQ-9 greater than or equal to 5) - proficiency in English - access to a smartphone and internet - ability to receive text messages

Exclusion Criteria

  • Prior experience with meditation - Prior use of the Healthy Minds Program app - History of psychosis or mania - Plans to travel in the next six weeks - Suicidal ideation or thoughts of self-harm indicated by PHQ-9 item 9 and BDI item 9 - Failure to select the correct code word mentioned in the welcome video - Not a US citizen - Non-permanent resident

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Factorial Assignment
Intervention Model Description
Participants are randomized to six different binary conditions. The investigators plan to collapse the groups for analysis, for example, combining participants with or without the introduction videos, regardless of their other assigned conditions.
Primary Purpose
Other
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Introduction Video to HMP app 		All participants are randomized to this condition (Yes or No)
  • Other: Healthy Minds Program (HMP) app
    All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no
    Other names:
    • HMP app
Experimental
Introduction Video to Training Modules 		All participants are randomized to this condition (Yes or No)
  • Other: Healthy Minds Program (HMP) app
    All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no
    Other names:
    • HMP app
Experimental
Module Order based on ACIP Score 		All participants are randomized to this condition (Highest score first or Lowest score first)
  • Other: Healthy Minds Program (HMP) app
    All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no
    Other names:
    • HMP app
Experimental
Practice-Nudging Test Messages 		All participants are randomized to this condition (Yes or No)
  • Other: Healthy Minds Program (HMP) app
    All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no
    Other names:
    • HMP app
Experimental
Microsupport Messages During Intervention 		All participants are randomized to this condition (Yes or No)
  • Other: Healthy Minds Program (HMP) app
    All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no
    Other names:
    • HMP app
Experimental
Microsupport Messages During Follow-Up 		All participants are randomized to this condition (Yes or No)
  • Other: Healthy Minds Program (HMP) app
    All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no
    Other names:
    • HMP app

Recruiting Locations

Center for Healthy Minds
Madison 5261457, Wisconsin 5279468 53703
Contact:
Wendy Lau
608-890-3073
wendy.lau@wisc.edu

More Details

NCT ID
NCT07051330
Status
Recruiting
Sponsor
University of Wisconsin, Madison

Study Contact

Simon Goldberg, PhD
(608) 265-8986
sbgoldberg@wisc.edu

Detailed Description

Participants will be randomly assigned to various training conditions that vary across six factors. Each of the six factors is binary ("yes" vs. "no"), and for each factor there is a 50 percent probability of assignment to either level. 1. Introduction video for the app (yes / no) 2. Introduction video for the training modules (yes / no) 3. Module order based on ACIP score (highest-first / lowest-first) 4. Practice-nudging text messages (yes / no) 5. Microsupport messages during the intervention period (yes / no) 6. Microsupport messages during the follow-up period (yes / no) Participants will take surveys at baseline, weekly through the 4-week intervention, and 3-month follow-up.

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ResearchMatch is funded in part by the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program, led by the NIH’s National Center for Advancing Translational Sciences (NCATS), grants UL1TR000445 and 1U54RR032646-01, and grant U24TR001579 from NCATS and the National Library of Medicine. The content of this website is solely the responsibility of ResearchMatch and Vanderbilt University and does not necessarily represent the official views of the NIH, NCATS, or NLM.

Vanderbilt University Medical Center