Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy

Purpose

The goal of this project is to study how the brain reacts to a small electrical signal. Researchers will be using a novel combination of recording electrodes. The researchers will measure the brain response from these electrodes.

Condition

  • Intractable Epilepsy

Eligibility

Eligible Ages
Between 22 Years and 75 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus - Can provide informed consent for the study and willing to participate

Exclusion Criteria

  • Presence of a permanent electronic implant - Any chronic medical conditions that prevent safe placement of electrodes

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Basic Science
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Medication-intractable epilepsy
  • Device: stimulating probes and electrodes
    Subdural electrodes and/or ball tip probes will be used intraoperatively to provide electrical stimulation to the brain.

Recruiting Locations

University of Michigan
Ann Arbor, Michigan 48109
Contact:
Ron Ball
734-936-7010
rmball@umich.edu

More Details

NCT ID
NCT07014592
Status
Recruiting
Sponsor
University of Michigan

Study Contact

Ron Ball
734 936-7010
rmball@umich.edu