Relationships Between Exercise and Appetite in Women With Loss of Control Eating
Purpose
This pilot study is a first step in looking at the relationship between exercise and appetite in women with loss of control eating.
Conditions
- Eating Disorders
- Binge-Eating Disorder
- Bulimia Nervosa
Eligibility
- Eligible Ages
- Between 18 Years and 45 Years
- Eligible Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Engage in loss of control eating at least 12 times in the last three months - Clinically significant eating disorder-related impairment (CIA > 15) - Taking hormonal contraception - Minimum VO2max of 50th percentile for age and sex assigned at birth - Be willing to eat study-provided foods - Likes chocolate (at least 6/10 on 10 point scale)
Exclusion Criteria
- BMI < 18.5 kgm/2 - Medical conditions that affect appetite or weight (e.g., diabetes mellitus, thyroid disease) - Recent pregnancy or breastfeeding (prior 6 months) - Relevant food allergies (e.g., wheat, chocolate) - Specific phobia, blood-injection-injury type - Medical condition that precludes safe participation in exercise (e.g., stress fracture) - Medications that acutely affect appetite (e.g., GLP-1 agonists; psychiatric medications allowed)
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover Assignment
- Primary Purpose
- Basic Science
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Rest, Fed Exercise, Fasted Exercise |
At Study Visit 2, participants will eat breakfast and rest (abstain from exercise). At Study Visit 3, participants will eat breakfast and exercise. At Study Visit 4, participants will abstain from breakfast and will engage in exercise. |
|
|
Experimental Rest, Fasted Exercise, Fed Exercise |
At Study Visit 2, participants will eat breakfast and rest (abstain from exercise). At Study Visit 3, participants will abstain from breakfast and will engage in exercise. At Study Visit 4, participants will eat breakfast and exercise. |
|
|
Experimental Fed Exercise, Rest, Fasted Exercise |
At Study Visit 2, participants will eat breakfast and exercise. At Study Visit 3, participants will eat breakfast and rest (abstain from exercise). At Study Visit 4, participants will abstain from breakfast and will engage in exercise. |
|
|
Experimental Fed Exercise, Fasted Exercise, Rest |
At Study Visit 2, participants will eat breakfast and exercise. At Study Visit 3, participants will abstain from breakfast and will engage in exercise. At Study Visit 4, participants will eat breakfast and rest (abstain from exercise). |
|
|
Experimental Fasted Exercise, Fed Exercise, Rest |
At Study Visit 2, participants will abstain from breakfast and will engage in exercise. At Study Visit 3, participants will eat breakfast and exercise. At Study Visit 4, participants will eat breakfast and rest (abstain from exercise) |
|
|
Experimental Fasted Exercise, Rest, Fed Exercise |
At Study Visit 2, participants will abstain from breakfast and will engage in exercise. At Study Visit 3, participants will eat breakfast and rest (abstain from exercise). At Study Visit 4, participants will eat breakfast and exercise. |
|
Recruiting Locations
Ohio University
Athens 4505542, Ohio 5165418 45701
Athens 4505542, Ohio 5165418 45701
More Details
- NCT ID
- NCT06602973
- Status
- Recruiting
- Sponsor
- Ohio University