Trials Today

The main inclusion criteria include but are not limited to the following: - Has one of the following cancers: - Unresectable or metastatic colorectal cancer. - Advanced and/or unresectable biliary tract cancer (BTC) - Hepatocellular carcinoma (HCC) not amenable to locoregional therapy - Locally advanced unresectable or metastatic gastroesophageal cancer - Has received prior therapy for the cancer. - Has recovered from any side effects due to previous cancer treatment

The main exclusion criteria include but are not limited to the following: - Has a history of (noninfectious) interstitial lung disease (ILD) or pneumonitis that required steroids, or has current ILD or pneumonitis, and/or suspected ILD or pneumonitis that cannot be ruled out by standard diagnostic assessments at Screening - Has clinically severe respiratory compromise (based on the investigator's assessment) resulting from intercurrent pulmonary illnesses - Has evidence of any leptomeningeal disease - Has clinically significant corneal disease - Has uncontrolled, significant cardiovascular disease or cerebrovascular disease - Has evidence of ongoing uncontrolled systemic bacterial, fungal, or viral infection