Trials Today

include: Triple Negative Breast Cancer - ER/PR <10% and HER negative per current ASCO/CAP guidelines - Stages I-IV - Any age at diagnosis - Patient must be within 5 years of diagnosis - Eligible regardless of genetic testing status - Genetic testing recommended for patients meeting NCCN and Medicare guidelines AND/OR Germline mutation Carriers - Patients with deleterious or uncertain mutations in HBOC genes (BRCA, PTEN, P53, -PALB2 etc) are eligible regardless of type/site of cancer - Healthy patients harboring mutations also eligible - There is no time limit from the time of diagnosis of cancer and enrollment. - Eligible regardless of personal history of cancer

include: Triple Negative Breast Cancer -Patient is not within five years of diagnosis Germline mutation Carriers: -Patient only carries a HBOC mutation that is classified as "polymorphism" of "favor polymorphism"